Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Cdh2  cadherin 2   (Synonyms: Ncad, N-CAD, N-cadherin)
Results	Reference
1	J:125783 Baumer S, Keller L, Holtmann A, Funke R, August B, Gamp A, Wolburg H, Wolburg-Buchholz K, Deutsch U, Vestweber D, Vascular endothelial cell-specific phosphotyrosine phosphatase (VE-PTP) activity is required for blood vessel development. Blood. 2006 Jun 15;107(12):4754-62
1*	J:221094 Carracedo S, Sacher F, Brandes G, Braun U, Leitges M, Redundant role of protein kinase C delta and epsilon during mouse embryonic development. PLoS One. 2014;9(8):e103686
1	J:294824 Dias A, Lozovska A, Wymeersch FJ, Novoa A, Binagui-Casas A, Sobral D, Martins GG, Wilson V, Mallo M, A Tgfbr1/Snai1-dependent developmental module at the core of vertebrate axial elongation. Elife. 2020 Jun 29;9:e56615
1*	J:97177 Edsbagge J, Johansson JK, Esni F, Luo Y, Radice GL, Semb H, Vascular function and sphingosine-1-phosphate regulate development of the dorsal pancreatic mesenchyme. Development. 2005 Mar;132(5):1085-92
1*	J:72022 Esni F, Johansson BR, Radice GL, Semb H, Dorsal pancreas agenesis in N-cadherin- deficient mice. Dev Biol. 2001 Oct 1;238(1):202-12
1*	J:84816 Fagman H, Grande M, Edsbagge J, Semb H, Nilsson M, Expression of classical cadherins in thyroid development: maintenance of an epithelial phenotype throughout organogenesis. Endocrinology. 2003 Aug;144(8):3618-24
1	J:316286 Francou A, Saint-Michel E, Mesbah K, Kelly RG, TBX1 regulates epithelial polarity and dynamic basal filopodia in the second heart field. Development. 2014 Nov;141(22):4320-31
1	J:220469 Grego-Bessa J, Hildebrand J, Anderson KV, Morphogenesis of the mouse neural plate depends on distinct roles of cofilin 1 in apical and basal epithelial domains. Development. 2015 Apr 1;142(7):1305-14
1	J:301045 Guo SS, Au TYK, Wynn S, Aszodi A, Chan D, Fassler R, Cheah KSE, beta1 Integrin regulates convergent extension in mouse notogenesis, ensures notochord integrity and the morphogenesis of vertebrae and intervertebral discs. Development. 2020 Nov 18;147(22):dev192724
1*	J:155247 Hierholzer A, Kemler R, beta-catenin-mediated signaling and cell adhesion in postgastrulation mouse embryos. Dev Dyn. 2009 Aug 24;239(1):191-199
1	J:327185 Inubushi T, Nakanishi Y, Abe M, Takahata Y, Nishimura R, Kurosaka H, Irie F, Yamashiro T, Yamaguchi Y, The cell surface hyaluronidase TMEM2 plays an essential role in mouse neural crest cell development and survival. PLoS Genet. 2022 Jul;18(7):e1009765
1	J:305411 Jaffe E, Niswander L, Loss of Grhl3 is correlated with altered cellular protrusions in the non-neural ectoderm during neural tube closure. Dev Dyn. 2021 May;250(5):732-744
1*	J:297161 Javali A, Lakshmanan V, Palakodeti D, Sambasivan R, Modulation of beta-catenin levels regulates cranial neural crest patterning and dispersal into first pharyngeal arch. Dev Dyn. 2020 May 19;
1	J:310961 Junghans D, Herzog S, Cnn3 regulates neural tube morphogenesis and neuronal stem cell properties. FEBS J. 2018 Jan;285(2):325-338
1*	J:265502 Kim ST, Lee YJ, Tasaki T, Hwang J, Kang MJ, Yi EC, Kim BY, Kwon YT, The N-recognin UBR4 of the N-end rule pathway is required for neurogenesis and homeostasis of cell surface proteins. PLoS One. 2018;13(8):e0202260
1	J:330214 Lania G, Franzese M, Adachi N, Bilio M, Flore G, Russo A, D'Agostino E, Angelini C, Kelly RG, Baldini A, A phenotypic rescue approach identifies lineage regionalization defects in a mouse model of DiGeorge syndrome. Dis Model Mech. 2022 Sep 1;15(9):dmm049415
1	J:244791 Li CJ, Hong T, Tung YT, Yen YP, Hsu HC, Lu YL, Chang M, Nie Q, Chen JA, MicroRNA filters Hox temporal transcription noise to confer boundary formation in the spinal cord. Nat Commun. 2017 Mar 24;8:14685
1	J:231597 Li D, Sinha T, Ajima R, Seo HS, Yamaguchi TP, Wang J, Spatial regulation of cell cohesion by Wnt5a during second heart field progenitor deployment. Dev Biol. 2016 Apr 1;412(1):18-31
1	J:334073 Lin L, Pinto A, Wang L, Fukatsu K, Yin Y, Bamforth SD, Bronner ME, Evans SM, Nie S, Anderson RH, Terskikh AV, Grossfeld PD, ETS1 loss in mice impairs cardiac outflow tract septation via a cell migration defect autonomous to the neural crest. Hum Mol Genet. 2022 Dec 16;31(24):4217-4227
1	J:158385 Lindqvist M, Horn Z, Bryja V, Schulte G, Papachristou P, Ajima R, Dyberg C, Arenas E, Yamaguchi TP, Lagercrantz H, Ringstedt T, Vang-like protein 2 and Rac1 interact to regulate adherens junctions. J Cell Sci. 2010 Feb 1;123(Pt 3):472-83
1	J:264113 Lopez-Escobar B, Caro-Vega JM, Vijayraghavan DS, Plageman TF, Sanchez-Alcazar JA, Moreno RC, Savery D, Marquez-Rivas J, Davidson LA, Ybot-Gonzalez P, The non-canonical Wnt-PCP pathway shapes the mouse caudal neural plate. Development. 2018 May 8;145(9):dev157487
1	J:97478 Lu S, Borst DE, Horowits R, N-RAP expression during mouse heart development. Dev Dyn. 2005 May;233(1):201-12
1*	J:67158 Luo Y, Ferreira-Cornwell M, Baldwin H, Kostetskii I, Lenox J, Lieberman M, Radice G, Rescuing the N-cadherin knockout by cardiac-specific expression of N- or E-cadherin. Development. 2001 Feb;128(4):459-69
1	J:95209 Luo Y, Kostetskii I, Radice GL, N-cadherin is not essential for limb mesenchymal chondrogenesis. Dev Dyn. 2005 Feb;232(2):336-44
1	J:98422 Luo Y, Radice GL, N-cadherin acts upstream of VE-cadherin in controlling vascular morphogenesis. J Cell Biol. 2005 Apr 11;169(1):29-34
1	J:127463 Ma X, Bao J, Adelstein RS, Loss of cell adhesion causes hydrocephalus in nonmuscle myosin II-B-ablated and mutated mice. Mol Biol Cell. 2007 Jun;18(6):2305-12
1	J:320754 Martin-Lanneree S, Halliez S, Hirsch TZ, Hernandez-Rapp J, Passet B, Tomkiewicz C, Villa-Diaz A, Torres JM, Launay JM, Beringue V, Vilotte JL, Mouillet-Richard S, The Cellular Prion Protein Controls Notch Signaling in Neural Stem/Progenitor Cells. Stem Cells. 2017 Mar;35(3):754-765
1*	J:329537 Martinez Traverso IM, Steimle JD, Zhao X, Wang J, Martin JF, LATS1/2 control TGFB-directed epithelial-to-mesenchymal transition in the murine dorsal cranial neuroepithelium through YAP regulation. Development. 2022 Sep 15;149(18):dev200860
1	J:235736 Masek J, Machon O, Korinek V, Taketo MM, Kozmik Z, Tcf7l1 protects the anterior neural fold from adopting the neural crest fate. Development. 2016 Jun 15;143(12):2206-16
1	J:278347 Miao L, Li J, Li J, Lu Y, Shieh D, Mazurkiewicz JE, Barroso M, Schwarz JJ, Xin HB, Singer HA, Vincent PA, Zhong W, Radice GL, Wan LQ, Fan ZC, Huang G, Wu M, Cardiomyocyte orientation modulated by the Numb family proteins-N-cadherin axis is essential for ventricular wall morphogenesis. Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15560-15569
1	J:279661 Nikolopoulou E, Hirst CS, Galea G, Venturini C, Moulding D, Marshall AR, Rolo A, De Castro SCP, Copp AJ, Greene NDE, Spinal neural tube closure depends on regulation of surface ectoderm identity and biomechanics by Grhl2. Nat Commun. 2019 Jun 6;10(1):2487
1*	J:289913 Omotehara T, Wu X, Kuramasu M, Itoh M, Connection between seminiferous tubules and epididymal duct is originally induced before sex differentiation in a sex-independent manner. Dev Dyn. 2020 Jun;249(6):754-764
1*	J:41888 Packer AI, Elwell VA, Parnass JD, Knudsen KA, Wolgemuth DJ, N-cadherin protein distribution in normal embryos and in embryos carrying mutations in the homeobox gene Hoxa-4. Int J Dev Biol. 1997 Jun;41(3):459-68
1	J:292657 Pieters T, Sanders E, Tian H, van Hengel J, van Roy F, Neural defects caused by total and Wnt1-Cre mediated ablation of p120ctn in mice. BMC Dev Biol. 2020 Aug 3;20(1):17
1	J:331697 Ramachandran J, Zhou W, Bardenhagen AE, Nasr T, Yates ER, Zorn AM, Ji H, Vokes SA, Hedgehog regulation of epithelial cell state and morphogenesis in the larynx. Elife. 2022 Nov 18;11
1	J:228847 Ramsbottom SA, Sharma V, Rhee HJ, Eley L, Phillips HM, Rigby HF, Dean C, Chaudhry B, Henderson DJ, Vangl2-regulated polarisation of second heart field-derived cells is required for outflow tract lengthening during cardiac development. PLoS Genet. 2014 Dec;10(12):e1004871
1	J:128002 Rizzoti K, Lovell-Badge R, SOX3 activity during pharyngeal segmentation is required for craniofacial morphogenesis. Development. 2007 Oct;134(19):3437-48
1*	J:202837 Rowton M, Ramos P, Anderson DM, Rhee JM, Cunliffe HE, Rawls A, Regulation of mesenchymal-to-epithelial transition by PARAXIS during somitogenesis. Dev Dyn. 2013 Nov;242(11):1332-44
1	J:161883 Sasse P, Malan D, Fleischmann M, Roell W, Gustafsson E, Bostani T, Fan Y, Kolbe T, Breitbach M, Addicks K, Welz A, Brem G, Hescheler J, Aszodi A, Costell M, Bloch W, Fleischmann BK, Perlecan is critical for heart stability. Cardiovasc Res. 2008 Dec 1;80(3):435-44
1	J:158133 Smith AN, Miller LA, Radice G, Ashery-Padan R, Lang RA, Stage-dependent modes of Pax6-Sox2 epistasis regulate lens development and eye morphogenesis. Development. 2009 Sep;136(17):2977-85
1	J:309602 Soh BS, Buac K, Xu H, Li E, Ng SY, Wu H, Chmielowiec J, Jiang X, Bu L, Li RA, Cowan C, Chien KR, N-cadherin prevents the premature differentiation of anterior heart field progenitors in the pharyngeal mesodermal microenvironment. Cell Res. 2014 Dec;24(12):1420-32
1	J:229586 Tondeleir D, Noelanders R, Bakkali K, Ampe C, Beta-actin is required for proper mouse neural crest ontogeny. PLoS One. 2014;9(1):e85608
1*	J:65597 van Raamsdonk CD, Tilghman SM, Dosage requirement and allelic expression of PAX6 during lens placode formation. Development. 2000 Dec;127(24):5439-48
1*	J:131432 Wang Y, Lian L, Golden JA, Morrisey EE, Abrams CS, PIP5KI gamma is required for cardiovascular and neuronal development. Proc Natl Acad Sci U S A. 2007 Jul 10;104(28):11748-53
1	J:167065 Werth M, Walentin K, Aue A, Schonheit J, Wuebken A, Pode-Shakked N, Vilianovitch L, Erdmann B, Dekel B, Bader M, Barasch J, Rosenbauer F, Luft FC, Schmidt-Ott KM, The transcription factor grainyhead-like 2 regulates the molecular composition of the epithelial apical junctional complex. Development. 2010 Nov;137(22):3835-45
1	J:278242 Xia M, Luo W, Jin H, Yang Z, HAND2-mediated epithelial maintenance and integrity in cardiac outflow tract morphogenesis. Development. 2019 Jul 4;146(13):dev177477
1	J:99711 Yuan X, Zhou Y, Casanova E, Chai M, Kiss E, Grone HJ, Schutz G, Grummt I, Genetic inactivation of the transcription factor TIF-IA leads to nucleolar disruption, cell cycle arrest, and p53-mediated apoptosis. Mol Cell. 2005 Jul 1;19(1):77-87